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In this white paper, we explore the critical role of high-throughput quantification of antibody binding in the development of therapeutics targeting GPCRs. We will then discuss how Luminex's microspheres (beads) and fluorescent detection instruments enable multiplex immunoassays for screening GPCR-antibody interactions.
The human body constantly responds to external environmental changes through membrane proteins, with G protein-coupled receptors (GPCRs) being the largest family. GPCRs respond to a wide range of molecules, including lipids and therapeutic drugs, making them key targets for therapeutics.
Researchers have recently utilized Luminex’s xMAP® Technology for multiplex immunoassays to investigate these interactions, resulting in software that advances anti-GPCR therapeutic research.
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