Exploring the Future of Immune Response Measurement
We’re excited to share a thought-provoking article by our Senior Director of Scientific Affairs Programs, Dr. Sherry Dunbar, featured in The Pathologist. In "A Measured Response," Dr. Dunbar explores how bead-based multiplexing is shaping the future of immune response measurement, offering new possibilities for immunology and diagnostics. Learn how this innovative approach is transforming the field.
Explore the new ProcartaPlex™ Human MAPK pathway panels
Enhance your research with Invitrogen™ ProcartaPlex™ Human MAPK Pathway panels. These new panels enable the simultaneous detection and quantitation of six key proteins involved in the MAPK cell signaling pathway. With these panels, you can easily measure both total and phosphorylated proteins from a single sample, helping to streamline your workflow and providing comprehensive insights into cellular signaling events.
These new panels feature:
Six new analytes, including JNK1/3, p38, and c-Myc
Format flexibility with preconfigured panels, customization, and single-target analysis solutions
Combinability with existing cell signaling targets to design larger panels
New Paper: Unraveling protein and gene interactions involved in HIV research
Irrinki et al. investigated the use of structure-based drug design to create novel Protein kinase C (PKC) agonists for activation of latent HIV reservoirs, which help improve recognition and elimination of HIV-infected cells. (DOI: 10.1371/journal.ppat.1012874)
The group designed agonists with the goal to selectivity bind PKC- ε, reduce platelet toxicity, and strongly target latent HIV expression.The researchers carried out multiple experiments, including xMAP-based assays for protein and gene expression analysis. A custom Invitrogen™ QuantiGene™ Plex multiplex panel was designed to measure EGR1 and CD69 mRNA in rat blood throughout different timepoints after PKC agonist dosing. The Invitrogen™ ProcartaPlex™ NHP Cytokine/Chemokine/Growth Factor Panel, 37plex was used for plasma cytokine analysis of PKC agonist-dosed rhesus macaques across selected time points.
With the use of different protein and gene expression assays, the group was able to show that selective PKC isoform activation may open new avenues towards HIV therapeutic strategies.
New targets are now available on the Mouse Discovery Menu. Researchers can now explore over 100 analytes, including the newly added IL-9, sclerostin, and CXCL9, to support their mouse model studies. This expanded offering allows scientists to design custom panels tailored to their specific research needs, providing flexibility and precision for a wide range of applications. With the most versatile menu available, researchers can confidently select the right combination of analytes to gain deeper insights into their studies.
Advancing the Care of Critically Ill Patients with Multiplex Analysis
Discover how the Critical Care Research Group at the University of Queensland is pushing the boundaries of anticoagulation research in extracorporeal membrane oxygenation and cardiopulmonary bypass support. By leveraging R&D Systems xMAP-based assays, the team maximizes data collection from limited samples, enabling them to explore the effects of nitric oxide on coagulation and inflammation with precision and efficiency. These insights are critical in advancing life-saving treatments and improving patient outcomes in critical care settings.
Multiplex Immunoassay to Monitor Drug Toxicity in Renal Proximal Tubule Chips
Are you tired of traditional methods for monitoring drug toxicity in renal cells? Multiplex immunoassays offer a more efficient and effective approach! Learn more in this must-read Application Note.
Explore the Most Extensive Mouse Multiplex Panel for Superior Results
The new MILLIPLEX® Mouse Cytokine/Chemokine/Growth Factor Expanded Panel 1 is available in a convenient 41-plex fixed premix or a comprehensive 68-plex fixed premix panel, designed to simplify assay setup and reduce preparation time. Efficiently manage your samples by analyzing multiple targets with just 25 µL/well (1:2 diluted), allowing you to conserve valuable samples while maximizing data yield. Choose between same-day or overnight incubation options to seamlessly integrate into your workflow, enhancing productivity. With the proven lot-to-lot consistency of MILLIPLEX® Qualified assays, you can trust in the accuracy and reliability of your results.
Partner with CADI to Get the Custom Immunoassay Solution for Your Research Needs
When you do not have the time or resources to develop and manufacture an immunoassay for your target(s) of interest, our Custom Assay Development & Innovation (CADI) team is committed to delivering the solution for your research needs. Whether you require a MILLIPLEX® multiplex panel to broadly survey multiple analytes, femtogram/mL biomarker analysis using the SMC® ultrasensitive immunoassay platform, or single protein detection with a tried-and-true ELISAs, you can confidently expect a knowledgeable scientific partner to create an assay that generates reliable measurements to help drive your biomarker project from hypothesis to publication.
These products are for Research Use Only. Not for use in diagnostic procedures. Please contact Luminex at support@luminexcorp.com to obtain the appropriate product information for your country of residence.
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